A new experimental approach
to high blood pressure
and type 2 diabetes.

Local research study. One procedure.

High blood pressure and type 2 diabetes are two of the most common health conditions in the world. Left untreated, both conditions may get worse over time and can lead to serious health complications, such as heart disease, stroke, and nerve damage.1,2 Despite this, many people struggle to control their high blood pressure and type 2 diabetes through lifestyle changes and daily medications.

Doctors in Australia are conducting a new research study evaluating a minimally-invasive procedure that may reduce blood pressure and improve glucose control - without new medications.

About the MODUS Study

The purpose of this research study is to evaluate the safety of liver denervation, kidney denervation and a combination of both in a single procedure using the study device and to detect any improvement in blood pressure and blood sugar levels after the procedure.

High Blood Pressure & Type 2 Diabetes: The Role of Nerves

The nerves surrounding the renal arteries (which supply blood to the kidneys) are important in regulating blood pressure. Previous research has shown that disrupting the nerves in the renal artery can reduce blood pressure. The nerves in the liver arteries are an important regulator of blood sugar levels. Previous research has shown that disrupting the nerves in the hepatic artery (which supplies blood to the liver) may reduce the amount of blood sugar produced from the liver.

The Study Procedure

The procedure is performed through a small incision in the groin. A catheter is guided to the artery leading to the liver and/or kidney, depending on which area is being treated. Radiofrequency (heat) energy is delivered from the catheter to the surrounding nerves. This disrupts the nerves leading to the either the liver and/or kidneys. After the procedure is completed, the catheter is removed.

The experimental device is currently being offered through a new clinical research study, called the MODUS Study. If you are eligible and choose to join the study, you will receive the procedure and all study-related care from a participating doctor.

See If You Are Eligible

The MODUS Study is enrolling people ages 22 - 70 who have high blood pressure and type 2 diabetes. To see if you are eligible, and to get connected with your local study centre to learn more, please complete the questionnaire below.

  1. https://www.mayoclinic.org/diseases-conditions/high-blood-pressure/symptoms-causes/syc-20373410
  2. https://www.mayoclinic.org/diseases-conditions/type-2-diabetes/symptoms-causes/syc-20351193